| Pair Name | Berberine, Letrozole | ||
| Phytochemical Name | Berberine (PubChem CID: 2353 ) | ||
| Anticancer drug Name | Letrozole (PubChem CID: 3902 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Berberine, Letrozole | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Gene Regulation | Up-regulation | Expression | ROS1 | hsa6098 |
| In Vitro Model | MDA-MB-231 | Breast adenocarcinoma | Homo sapiens (Human) | CVCL_0062 |
| Result | Our results suggest that concomitant treatment of LTZ-BBR increases the efficacy of chemotherapeutic agents with low BBR concentrations, especially in chemo-resistant malignancies. | |||
| No. | Title | Href |
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| 1 | Synergistic Combination of Letrozole and Berberine in Ascorbic Acid-Stabilized AuNPs: A Promising Solution for Breast Cancer. Pharmaceuticals (Basel). 2023 Aug 3;16(8):1099. doi: 10.3390/ph16081099. | Click |
